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Presbyopia is specifically characterized by an age-related decline in the eye's ability to accommodate, or focus on, nearby objects. As people age, the lens of the eye becomes less flexible, making it harder to adjust focus for close-up tasks such as reading or doing detailed work. This is due to changes in the structure of the lens and the surrounding muscles that enable accommodation.

Unlike conditions such as nearsightedness, which primarily affects distance vision, presbyopia directly impacts the ability to see clearly at close range due to the loss of flexibility in the lens. Additionally, it is distinct from conditions affecting night vision or overall distance vision, emphasizing its unique nature as related to aging and accommodation specifically.